Endocrine Abstracts

Histamine receptor antagonists seem to have effect on bone metabolism according to previous studies. We investigated the bone turnover in allergic children who were treated with H1 hisztamin receptor (H1R) antagonists.The biochemical bone turnover markers [β-CrossLapps (β-CTx), osteocalcin (OCN), β-CTx/OCN ratio], parathyroid hormone (PTH) and the 25-OH-vitamin D3 were determined in 37 H1R antagonist treated multiplex allergic c...

A 32-year-old women initially presented with recurrent kidney stones and was found to have nephrocalcinosis. She was found to normocalcaemic but hypercalciuric, with a plasma ionized calcium at upper-limit of normal and a PTH in lower normal range. One year later, during the first trimester of a pregnancy, she presented with severe hypercalcaemia, hypercalciuria and suppression of PTH. Extensive investigations for causes of hypercalcaemia excluded hyperparathyroidism, other en...